BCHM 451 (cross listed as MBMB 451 and CHEM 451) is a two semester biochemistry course providing a thorough introduction to modern biochemistry for undergraduate and graduate students. BCHM 451a is devoted to structural biology, molecular biology, and cell biology, while BCHM 451b is devoted to enzymes, carbohydrate metabolism, membranes, lipid metabolism, amino acid metabolism, and nucleotide metabolism. Students should be familiar with basic concepts in organic and physical chemistry as well as quantitative approaches to problem solving.
COURSE OUTLINE:
First Section: Nucleic Acids and Their Expression
Chapter 1: Introduction Chapter 5: Nucleic Acids, Gene Expression, and Recombinant DNA Technology Chapter 6: Techniques of Protein and Nucleic Acids Chapter 7: Covalent Structures of Proteins and Nucleic Acids Chapter 29: Nucleic Acid Structures Chapter 31: Transcription Chapter 34: Gene ExpressionExam I
Instructor: Blaine Bartholomew ( bbartholomew@siumed.edu )
Second Section: DNA and Protein Synthesis
Exam IIInstructor: Joseph Schmit ( jschmit@siumed.edu )
Third Section: Protein Structure/Function and Bioenergetics
Exam III Instructor: Peter Hardwicke ( phardwicke@siumed.edu )
MEETING TIME and PLACE:
Class meets twice a week on Tuesdays and Thursdays from 12:35-1:50 pm in Life Science III Auditorium.
RESOURCES:
The primary text for this
course is: Biochemistry by Voet and Voet. (Wiley Publishers,
2004, ISBN 0-471-19350-x)
Additional texts that you may find useful include:
Genes VIII by Lewin (Pearson Prentice Hall, 2004, ISBN 0-13-145140-5)
Check out www.prenhall.com/lewin
It is always a good idea to consult as many sources as possible. There are many different ways to present the same material, and a different view can often be very enlightening. We highly recommend it!
EXAM SCHEDULE: all exams will be held in LSIII Auditorium
Exam I on Section I: Thursday September 23, 2004 (12:35-1:50 PM)
Exam II on Section II: Thursday October 28, 2004 (12:35-1:50PM)
Exam III on Section III: Thursday December 9, 2004 (12:35-1:50 PM)
Final Exam (Comprehensive): Friday December 17, 2004 (12:50-2:50 PM)
GRADING POLICY:
Your performance in this course will be based on three exams plus a comprehensive final exam. Exams may consist of a combination of short-answer, multiple-choice, and problem-solving questions. Tests are scheduled to occur following seven to eight lectures. The lowest of the three exam scores will be dropped and each exam is worth 100 points. The comprehensive final exam is worth 200 points for a total possible of 400 points. The final exam will occur on the University's designated final exam day and time.
Letter grades will be assigned as follows:
A = 90 - 100%
B = 80 - 89%
C = 70 - 79%
D = 60 - 69%
F = 0 - 59%
Performance on problem sets and quizzes will be used to decide the grade for students whose cumulative scores fall on the borderline.
Comments and questions related to this web site should be directed to: bbartholomew@siumed.edu
SIUC/Molecular Biology, Microbiology and Biochemistry /URL: http://www.siu.edu/~mbmb
Last updated: September 8, 2004 / bb