Method of Medical Treatment of Alzheimer's Disease
Project Leaders: Robert E. Becker and Ezio Giacobini
Unit: School of Medicine, Springfield
Brief Description:
This invention relates to a method for improving memory and accompanying symptoms in patients with Alzheimer's disease and related disorders of memory. The method includes the steps of dosing a patient with 2,2-dichlorovinyl dimethyl phosphate (sometimes referred to as dichlorvos or DDVP) or a precursor thereof, maintaining said dosage at a level and over a period of time sufficient to create a concentration of DDVP in the brain whereby memory improvement occurs.
Patent Status:
U.S. Patent No. 4,950,658, issued Aug. 21, 1990.
Potential Commercial Uses:
Suitable for use as a drug therapy for the treatment of Alzheimer's disease. Some advanced clinical trial data is available.
Contact:
Rob Patino, SIU School of Medicine Office of Technology Transfer, (217) 545-8167, fax: (217) 545-0786