Soy Phytoestrogens:
Effects on Mammalian Reproduction

Objectives:

Our overall objective is to determine the effects of soy-related phytoestrogens on mammalian reproductive system differentiation and function.

Specific Aims:

1. To determine the effects of phytoestrogens on steroidogenesis (ovarian health) and apoptosis (ovulation propensity) in cultured primary granulosa cells from porcine ovaries .

2. To determine the effects of phytoestrogens on the reproduction of rats and pigs fed these soy products.

3. To determine the kinetics of specific phytoestrogen binding to an estrogen receptor and the effects soy-related phytoestrogens have on cell proliferation and apoptosis (programmed cell death) in cultured primary cells derived from fetal porcine reproductive progenitor organs.

Research Progress

August, 1996
June, 1997
August, 1998
March, 1999

SSR Abstract 1998

Soy Swine Nutrition Research Project

National Soybean Research Laboratory
Soy / Swine Nutrition Workshop, September 29-30, 1997
Workshop Intent/Workshop Agenda/Workshop Participants/
Workshop Results/Workshop Pictures
Soy Phytoestrogens: Analysis in Soybeans and Effects on Swine Reproduction
National Soybean Research Laboratory Lecture, November 19, 1996

Research on Phytoestrogens in Soybeans Could Have Impact on Swine Industry
NSRL Bulletin 4(1):February 1997

Related Research Projects

Soy Phytoestrogens and Cardiovascular Health
Gene Mapping of Phytoestrogen-Related Genes in Soybeans
Soy Phytoestrogens and Aging
Soy Phytoestrogens and Breast Cancer
Estrogen and Swine Reproductive Differentiation
Doisynolic Acids and Metabolism

~~~~~Revised 3/23/99~~~~~ TAW